human RPA4 shRNA silencing AAV

Name 
AAV-h-RPA4-shRNA
Cat No 
shAAV-221537
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RPA4.

shAAV-221537
AAV-h-RPA4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RPA4 (replication protein A4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HSU24186
Description (Vector)
RPA4 encodes a single-stranded DNA-binding protein that is the 30-kDa subunit of the replication protein A complex. Replication protein A is an essential factor for DNA double-strand break repair and cell cycle checkpoint activation. The encoded protein localizes to DNA repair foci and may be involved in the cellular DNA damage response. This protein may also play a role in inhibiting viral replication.
Gene ID
29935
Gene Name (Vector)
replication protein A4
Gene Symbol
RPA4
HGNC ID
HGNC:30305
ORF Size (aa)
786
RefSeq ID
NM_013347
RefSeq Synonyms
NM_013347, BC104014, BC104013, BC069824, BC069808, BC069791,
Species
human
UniGene ID
Hs.659349

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.