human RNASEH2B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human RNASEH2B.
shAAV-221307
AAV-h-RNASEH2B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human RNASEH2B (ribonuclease H2 subunit B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AGS2; DLEU8
Description (Vector)
RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2).
Gene ID
79621
Gene Name (Vector)
ribonuclease H2 subunit B
Gene Symbol
RNASEH2B
HGNC ID
HGNC:25671
ORF Size (aa)
996
RefSeq ID
NM_024570
RefSeq Synonyms
NM_024570, NM_001142279, BC036744,
Species
human
UniGene ID
Hs.306291
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.