human RIT1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human RIT1.
shAAV-221265
AAV-h-RIT1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human RIT1 (Ras like without CAAX 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
NS8; RIBB; RIT; ROC1
Description (Vector)
RIT1 encodes a member of a subfamily of Ras-related GTPases. The encoded protein is involved in regulating p38 MAPK-dependent signaling cascades related to cellular stress. This protein also cooperates with nerve growth factor to promote neuronal development and regeneration. Alternate splicing results in multiple transcript variants.
Gene ID
6016
Gene Name (Vector)
Ras like without CAAX 1
Gene Symbol
RIT1
HGNC ID
HGNC:10023
ORF Size (aa)
660
RefSeq ID
NM_006912
RefSeq Synonyms
NM_006912, NM_001256821, NM_001256820, BC104187, BC104186,
Species
human
UniGene ID
Hs.491234
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.