human RILP shRNA silencing AAV

Name 
AAV-h-RILP-shRNA
Cat No 
shAAV-221228
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RILP.

shAAV-221228
AAV-h-RILP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RILP (Rab interacting lysosomal protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PP10141
Description (Vector)
RILP encodes a lysosomal protein that interacts with RAB7, a small GTPase that controls transport to endocytic degradative compartments. Studies using mutant forms of the two proteins suggest that this protein represents a downstream effector for RAB7, and both proteins act together in the regulation of late endocytic traffic. A unique region of this protein has also been shown to be involved in the regulation of lysosomal morphology.
Gene ID
83547
Gene Name (Vector)
Rab interacting lysosomal protein
Gene Symbol
RILP
HGNC ID
HGNC:30266
ORF Size (aa)
1206
ORF Size (bp)
1206 bp
RefSeq ID
NM_031430
RefSeq Synonyms
NM_031430, BC031621,
Species
human
UniGene ID
Hs.534497

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.