human RGN shRNA silencing AAV

Name 
AAV-h-RGN-shRNA
Cat No 
shAAV-221097
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RGN.

shAAV-221097
AAV-h-RGN-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RGN (regucalcin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GNL; HEL-S-41; RC; SMP30
Description (Vector)
RGN is a highly conserved, calcium-binding protein, that is preferentially expressed in the liver and kidney. It may have an important role in calcium homeostasis. Studies in rat indicate that this protein may also play a role in aging, as it shows age-associated down-regulation. This gene is part of a gene cluster on chromosome Xp11.3-Xp11.23. Alternative splicing results in two transcript variants having different 5' UTRs, but encoding the same protein.
Gene ID
9104
Gene Name (Vector)
regucalcin
Gene Symbol
RGN
HGNC ID
HGNC:9989
ORF Size (aa)
684
RefSeq ID
NM_004683
RefSeq Synonyms
NM_152869, NM_004683, NM_001282849, NM_001282848, BC073173, BC050371,
Species
human
UniGene ID
Hs.77854

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.