Promotional banner reading 'FALL SAVINGS' with expiry date August 31 on an orange background; features a group of people with orange stacked blocks on the right and discounts for services and catalog products.

human RG9MTD1 shRNA silencing AAV

Name 
AAV-h-RG9MTD1-shRNA
Cat No 
shAAV-221079
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TRMT10C.

shAAV-221079
AAV-h-RG9MTD1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TRMT10C (tRNA methyltransferase 10C, mitochondrial RNase P subunit). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
COXPD30; HBV pre-S2 trans-regulated protein 2; HNYA; mitochondrial ribonuclease P protein 1; Mitochondrial RNase P protein 1; mitochondrial RNase P subunit 1; mRNA methyladenosine-N(1)-methyltransferase; MRPP1; renal carcinoma antigen NY-REN-49; RG9MTD1; RNA (guanine-9-) methyltransferase domain containing 1; RNA-(guanine-9-)-methyltransferase domain-containing protein 1; tRNA (adenine(9)-N(1))-methyltransferase; tRNA (guanine(9)-N(1))-methyltransferase; tRNA methyltransferase 10 homolog C; tRNA-(adenine(9)-N(1))-methyltransferase; tRNA-(guanine(9)-N(1))-methyltransferase
Description (eCommerce)
Mitochondrial ribonuclease P protein 1 (MRPP1) functions in mitochondrial tRNA maturation. MRPP1 is part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q7L0Y3].
Gene ID
54931
Gene Name (eCommerce)
tRNA methyltransferase 10C, mitochondrial RNase P subunit
Gene Name (Vector)
tRNA methyltransferase 10C, mitochondrial RNase P subunit
Gene Symbol
TRMT10C
HGNC ID
HGNC:26022
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1194
ORF Size (bp)
1194 bp
Protein Name (eCommerce)
Mitochondrial ribonuclease P protein 1
RefSeq ID
NM_017819
RefSeq Synonyms
NM_017819, BC035967,
Research Areas
Methyltransferase,Mitochondrion,RNA Processing
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
Mitochondrial ribonuclease P protein 1 (MRPP1) functions in mitochondrial tRNA maturation. MRPP1 is part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q7L0Y3].
UniGene ID
Hs.715724
UniProt ID (eCommerce)
Q7L0Y3

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.