human RFX3 shRNA silencing AAV

Name 
AAV-h-RFX3-shRNA
Cat No 
shAAV-221070
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RFX3.

shAAV-221070
AAV-h-RFX3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RFX3 (regulatory factor X3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
50
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
RFX3 is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Two transcript variants encoding different isoforms have been described for this gene, and at least one of the variants utilizes alternative polyadenylation signals.
Gene ID
5991
Gene Name (Vector)
regulatory factor X3
Gene Symbol
RFX3
HGNC ID
HGNC:9984
ORF Size (aa)
1242
ORF Size (bp)
1242 bp
RefSeq ID
NM_002919
RefSeq Synonyms
NM_134428, NM_002919, NM_001282117, NM_001282116, BC067778, BC022191,
Species
human
UniGene ID
Hs.136829

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.