human REC8 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human REC8.
shAAV-220972
AAV-h-REC8-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human REC8 (REC8 meiotic recombination protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HR21spB; REC8L1; Rec8p
Description (Vector)
REC8 encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.
Gene ID
9985
Gene Name (Vector)
REC8 meiotic recombination protein
Gene Symbol
REC8
HGNC ID
HGNC:16879
ORF Size (aa)
1644
ORF Size (bp)
1644 bp
RefSeq ID
NM_005132
RefSeq Synonyms
NM_005132, NM_001048205, BC010887, BC004159,
Species
human
UniGene ID
Hs.419259
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.