human RD3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human RD3.
shAAV-220955
AAV-h-RD3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human RD3 (retinal degeneration 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C1orf36; LCA12
Description (Vector)
RD3 encodes a retinal protein that is associated with promyelocytic leukemia-gene product (PML) bodies in the nucleus. Mutations in this gene cause Leber congenital amaurosis type 12, a disease that results in retinal degeneration. Alternative splicing results in multiple transcript variants.
Gene ID
343035
Gene Name (Vector)
retinal degeneration 3
Gene Symbol
RD3
HGNC ID
HGNC:19689
ORF Size (aa)
588
RefSeq ID
NM_183059
RefSeq Synonyms
NM_183059, NM_001164688, BC065541,
Species
human
UniGene ID
Hs.632495
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.