human RCVRN shRNA silencing AAV

Name
AAV-h-RCVRN-shRNA

Cat No
shAAV-220954

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human RCVRN.

shAAV-220954

AAV-h-RCVRN-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RCVRN (recoverin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

RCV1

Description (Vector)

RCVRN encodes a member of the recoverin family of neuronal calcium sensors. The encoded protein contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy.

Gene ID

5957

Gene Name (Vector)

recoverin

Gene Symbol

RCVRN

HGNC ID

HGNC:9937

ORF Size (aa)

603

RefSeq ID

NM_002903

RefSeq Synonyms

NM_002903, BC001720,

Species

human

UniGene ID

Hs.80539

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.