human RBMY1B shRNA silencing AAV

Name 
AAV-h-RBMY1B-shRNA
Cat No 
shAAV-220906
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RBMY1B.

shAAV-220906
AAV-h-RBMY1B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RBMY1B (RNA binding motif protein, Y-linked, family 1, member B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
RBMY1B encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. Multiple copies of this gene are found in the AZFb azoospermia factor region of chromosome Y and the encoded protein is thought to be involved in spermatogenesis. Most copies of this locus are pseudogenes, although six highly similar copies have full-length ORFs and are considered functional. Four functional copies of this gene are found within inverted repeat IR2; two functional copies of this gene are found in palindrome P3, along with two copies of PTPN13-like, Y-linked.
Gene ID
378948
Gene Name (Vector)
RNA binding motif protein, Y-linked, family 1, member B
Gene Symbol
RBMY1B
HGNC ID
HGNC:23914
ORF Size (aa)
1491
ORF Size (bp)
1491 bp
RefSeq ID
NM_001006121
RefSeq Synonyms
NM_001320948, NM_001006121, BC144577,
Species
human
UniGene ID
Hs.536001

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.