human RAD54L2 shRNA silencing AAV

Name
AAV-h-RAD54L2-shRNA

Cat No
shAAV-220654

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human RAD54L2.

shAAV-220654

AAV-h-RAD54L2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RAD54L2 (RAD54-like 2 (S. cerevisiae)). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

80

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

androgen receptor-interacting protein 4; AR interacting protein 4; ARIP4; helicase ARIP4; HSPC325; RAD54-like protein 2; SRISNF2L

Description (eCommerce)

ARIP4 (androgen-interacting protein 4) was identified in a yeast two-hybrid screen using the human androgen receptor (AR) as bait. It was found to be a member of the SNF2 (sucrose nonfermenting 2) protein family and to have ATPase activity. ARIP4 is able to activate AR-dependent transcription. Targeted inactivation of ARIP4 results in embryonic lethality and reduced growth potential of embryonic fibroblast. These findings indicate an important role in development and proliferation.

Gene ID

23132

Gene Name (eCommerce)

RAD54 like 2

Gene Name (Vector)

RAD54-like 2 (S. cerevisiae)

Gene Symbol

RAD54L2

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

4080

ORF Size (bp)

4080 bp

Protein Name (eCommerce)

Helicase ARIP4

RefSeq ID

NM_015106

RefSeq Synonyms

NM_015106, NM_001322257, NM_001322256, NM_001322253, BC024298,

Research Areas

Helicase Activity,Nuclear Receptor Coactivators

Research Areas (Faceted)

cell_biology

Species

human

Target Sentence

ARIP4 (androgen-interacting protein 4) was identified in a yeast two-hybrid screen using the human androgen receptor (AR) as bait. It was found to be a member of the SNF2 (sucrose nonfermenting 2) protein family and to have ATPase activity. ARIP4 is able to activate AR-dependent transcription. Targeted inactivation of ARIP4 results in embryonic lethality and reduced growth potential of embryonic fibroblast. These findings indicate an important role in development and proliferation.

UniGene ID

Hs.105399

UniProt ID (eCommerce)

Q9Y4B4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.