human RAB34 shRNA silencing AAV

Name
AAV-h-RAB34-shRNA

Cat No
shAAV-220537

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human RAB34.

shAAV-220537

AAV-h-RAB34-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RAB34 (RAB34, member RAS oncogene family). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

RAB39; RAH

Description (Vector)

RAB34 encodes a protein belonging to the RAB family of proteins, which are small GTPases involved in protein transport. This family member is a Golgi-bound member of the secretory pathway that is involved in the repositioning of lysosomes and the activation of macropinocytosis. Alternative splicing of this gene results in multiple transcript variants. RAB34 overlaps and shares exon structure with the nine-amino acid residue-repeats (NARR) gene, which encodes a functionally distinct nucleolar protein from a different reading frame.

Gene ID

83871

Gene Name (Vector)

RAB34, member RAS oncogene family

Gene Symbol

RAB34

HGNC ID

HGNC:16519

ORF Size (aa)

780

RefSeq ID

NM_031934

RefSeq Synonyms

NM_031934, NM_001256278, NM_001256277, NM_001256276, NM_001144943, NM_001144942, NM_001142625, NM_001142624, BC091510, BC066904, BC016841,

Species

human

UniGene ID

Hs.301853

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.