human RAB11B shRNA silencing AAV

Name
AAV-h-RAB11B-shRNA

Cat No
shAAV-220491

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human RAB11B.

shAAV-220491

AAV-h-RAB11B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RAB11B (RAB11B, member RAS oncogene family). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

H-YPT3

Description (Vector)

The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 (PubMed 7811277)).(supplied by OMIM, Nov 2010)

Gene ID

9230

Gene Name (Vector)

RAB11B, member RAS oncogene family

Gene Symbol

RAB11B

HGNC ID

HGNC:9761

ORF Size (aa)

657

RefSeq ID

NM_004218

RefSeq Synonyms

NM_004218, BC110081,

Species

human

UniGene ID

Hs.626404

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.