human PYGO2 shRNA silencing AAV

Name
AAV-h-PYGO2-shRNA

Cat No
shAAV-220455

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human PYGO2.

shAAV-220455

AAV-h-PYGO2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PYGO2 (pygopus family PHD finger 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

1190004M21Rik; pygopus 2; pygopus homolog 2

Description (eCommerce)

Pygo 2 is a member of the Pygopus family of genes first identified in Drosophila. Two pygo genes exist in mammals: Pygo1 and Pygo2. Pygo genes have been found to be involved in the regulation of Wnt signaling.

Gene ID

90780

Gene Name (eCommerce)

pygopus family PHD finger 2

Gene Name (Vector)

pygopus family PHD finger 2

Gene Symbol

PYGO2

HGNC ID

HGNC:30257

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1221

ORF Size (bp)

1221 bp

Protein Name (eCommerce)

Pygopus homolog 2

RefSeq ID

NM_138300

RefSeq Synonyms

NM_138300, BC032099, BC006132,

Research Areas

Brain Development,Histone Modification,Neurobiology,Neurodevelopment,Signal Transduction,Wnt Signaling,Zinc-finger

Research Areas (Faceted)

cell_biology,developmental_biology,neurobiology,signal_transduction

Species

human

Target Sentence

Pygo 2 is a member of the Pygopus family of genes first identified in Drosophila. Two pygo genes exist in mammals: Pygo1 and Pygo2. Pygo genes have been found to be involved in the regulation of Wnt signaling.

UniGene ID

Hs.533597

UniProt ID (eCommerce)

Q9BRQ0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.