human PXDN shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-220427
Availability:
4-5 weeks
Name:
AAV-h-PXDN-shRNA
This is an AAV expressing shRNA for silencing of Human PXDN.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- PXDN
- Gene Name
- peroxidasin
- Gene ID
- 7837
- Gene Synonyms
- COPOA; D2S448; D2S448E; MG50; PRG2; PXN; VPO
- ORF Size
- 4437 bp
- RefSeq#
- NM_012293
- Gene Description
- Drosophila peroxidasin is an extracellular matrix-associated peroxidase (Horikoshi et al., 1999 (PubMed 10441517)). It is expressed exclusively in hemocytes derived from head mesoderm at a very early stage of differentiation. Peroxidasin exists as a homotrimer with a unique hybrid structure that combines an enzymatically functional peroxidase domain with motifs that are typically found in extracellular matrix-associated proteins. It is a secreted protein that contains a secretory recognition sequence at its N terminus. Peroxidasin catalyzes hydrogen peroxide-driven radioiodination, oxidations, and the formation of dityrosine in vitro. It is also thought to function in extracellular matrix consolidation, phagocytosis, and defense.(supplied by OMIM, Jul 2009)
- UniGene ID
- Hs.332197
- HGNC ID
- HGNC:14966
Related Products
Product | Cat No. |
---|---|
Ad-h-PXDN | ADV-220427 |
Ad-m-PXDN | ADV-269886 |
AAV-m-PXDN-shRNA | shAAV-269886 |
Ad-h-PXDN-shRNA | shADV-220427 |
Ad-m-PXDN-shRNA | shADV-269886 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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