human PSTPIP1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PSTPIP1.
shAAV-220201
AAV-h-PSTPIP1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PSTPIP1 (proline-serine-threonine phosphatase interacting protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD2BP1; CD2BP1L; CD2BP1S; H-PIP; PAPAS; PSTPIP
Description (Vector)
PSTPIP1 binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.
Gene ID
9051
Gene Name (Vector)
proline-serine-threonine phosphatase interacting protein 1
Gene Symbol
PSTPIP1
HGNC ID
HGNC:9580
ORF Size (aa)
1251
ORF Size (bp)
1251 bp
RefSeq ID
NM_003978
RefSeq Synonyms
NM_003978, NM_001321137, NM_001321136, NM_001321135, BC008602,
Species
human
UniGene ID
Hs.129758
Recently Viewed Products
Ad-CMV-Luc
Cat No: 1000
Ad-CMV-Akt1 (Myr)
Cat No: 1020
Ad-CMV-Akt1 (dn)
Cat No: 1021
Ad-CMV-Akt1 (wt)
Cat No: 1022
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.