human PSMA4 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PSMA4.
shAAV-220101
AAV-h-PSMA4-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PSMA4 (proteasome subunit alpha 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HC9; HsT17706; PSC9
Description (Vector)
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
5685
Gene Name (Vector)
proteasome subunit alpha 4
Gene Symbol
PSMA4
HGNC ID
HGNC:9533
ORF Size (aa)
573
RefSeq ID
NM_002789
RefSeq Synonyms
NM_002789, NM_001330676, NM_001330675, NM_001330673, NM_001102668, NM_001102667, BC093069, BC056249, BC047667, BC022445, BC005361,
Species
human
UniGene ID
Hs.251531
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.