human PRTFDC1 shRNA silencing AAV

Name 
AAV-h-PRTFDC1-shRNA
Cat No 
shAAV-220038
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PRTFDC1.

shAAV-220038
AAV-h-PRTFDC1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PRTFDC1 (phosphoribosyl transferase domain containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HHGP; phosphoribosyltransferase domain-containing protein 1
Description (eCommerce)
Phosphoribosyltransferase domain-containing protein 1 (PRTFDC1) has low, barely detectable phosphoribosyltransferase activity (in vitro). PRTFDC1 binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NRG1].
Gene ID
56952
Gene Name (eCommerce)
phosphoribosyl transferase domain containing 1
Gene Name (Vector)
phosphoribosyl transferase domain containing 1
Gene Symbol
PRTFDC1
HGNC ID
HGNC:23333
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
678
ORF Size (bp)
678 bp
Protein Name (eCommerce)
Phosphoribosyltransferase domain-containing protein 1
RefSeq ID
NM_020200
RefSeq Synonyms
NM_020200, NM_001282786, BC008662,
Research Areas
Cell Biology,Metabolism/Metabolic Process
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
Phosphoribosyltransferase domain-containing protein 1 (PRTFDC1) has low, barely detectable phosphoribosyltransferase activity (in vitro). PRTFDC1 binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NRG1].
UniGene ID
Hs.405619
UniProt ID (eCommerce)
Q9NRG1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.