human PRODH shRNA silencing AAV

Cat. No: shAAV-219924

Availability: 6-8 weeks

Name: AAV-h-PRODH-shRNA

This is an AAV expressing shRNA for silencing of Human PRODH.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PRODH
Gene Name: proline dehydrogenase 1
Gene ID: 5625
Gene Synonyms: HSPOX2; PIG6; POX; PRODH1; PRODH2; TP53I6
ORF Size: 1479 bp
RefSeq#: NM_016335
Gene Description: PRODH encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). PRODH is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.517352
HGNC ID: HGNC:9453