human PRND shRNA silencing AAV

Name 
AAV-h-PRND-shRNA
Cat No 
shAAV-219910
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PRND.

shAAV-219910
AAV-h-PRND-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PRND (prion protein 2 (dublet)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
dJ1068H6.4; DOPPEL; DPL; PrPLP
Description (Vector)
PRND is found on chromosome 20, approximately 20 kbp downstream of the gene encoding cellular prion protein, to which it is biochemically and structurally similar. The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that is found predominantly in testis. Mutations in this gene may lead to neurological disorders.
Gene ID
23627
Gene Name (Vector)
prion protein 2 (dublet)
Gene Symbol
PRND
HGNC ID
HGNC:15748
ORF Size (aa)
531
RefSeq ID
NM_012409
RefSeq Synonyms
NM_012409, BC043644,
Species
human
UniGene ID
Hs.406696

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.