human PRMT8 shRNA silencing AAV

Name
AAV-h-PRMT8-shRNA

Cat No
shAAV-219909

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human PRMT8.

shAAV-219909

AAV-h-PRMT8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PRMT8 (protein arginine methyltransferase 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HRMT1L3; HRMT1L4

Description (Vector)

Arginine methylation is a widespread posttranslational modification mediated by arginine methyltransferases, such as PRMT8. Arginine methylation is involved in a number of cellular processes, including DNA repair, RNA transcription, signal transduction, protein compartmentalization, and possibly protein translation (Lee et al., 2005 (PubMed 16051612)).(supplied by OMIM, Mar 2008)

Gene ID

56341

Gene Name (Vector)

protein arginine methyltransferase 8

Gene Symbol

PRMT8

HGNC ID

HGNC:5188

ORF Size (aa)

1185

ORF Size (bp)

1185 bp

RefSeq ID

NM_019854

RefSeq Synonyms

NM_019854, NM_001256536, BC022458,

Species

human

UniGene ID

Hs.504530

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.