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human PRMT3 shRNA silencing AAV

Name 
AAV-h-PRMT3-shRNA
Cat No 
shAAV-219902
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PRMT3.

shAAV-219902
AAV-h-PRMT3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PRMT3 (protein arginine methyltransferase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3; HMT1 hnRNP methyltransferase-like 3; HRMT1L3; protein arginine N-methyltransferase 3
Description (eCommerce)
Protein arginine methyltransferase 3 (PRMT3) catalyzes the mono and asymmetric dimethylation of the guanidino nitrogens of arginyl residues of some proteins.
Description (Vector)
Type I protein arginine N-methyltransferases (PRMTs), such as PRMT3, catalyze the formation of asymmetric N(G),N(G)-dimethylarginine (ADMA) residues in proteins (Tang et al., 1998 (PubMed 9642256)).(supplied by OMIM, Mar 2008)
Gene ID
10196
Gene Name (eCommerce)
protein arginine methyltransferase 3
Gene Name (Vector)
protein arginine methyltransferase 3
Gene Symbol
PRMT3
HGNC ID
HGNC:30163
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1596
ORF Size (bp)
1596 bp
Protein Name (eCommerce)
Protein arginine N-methyltransferase 3
RefSeq ID
NM_005788
RefSeq Synonyms
NM_005788, NM_001145167, NM_001145166, BC064831, BC037544,
Research Areas
Metabolism/Metabolic Process,Methyltransferase,Neurobiology,Zinc-finger
Research Areas (Faceted)
metabolism,cell_biology,neurobiology
Species
human
Target Sentence
Protein arginine methyltransferase 3 (PRMT3) catalyzes the mono and asymmetric dimethylation of the guanidino nitrogens of arginyl residues of some proteins.
UniGene ID
Hs.152337
UniProt ID (eCommerce)
O60678

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.