human PRKAR1B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PRKAR1B.
shAAV-219853
AAV-h-PRKAR1B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PRKAR1B (protein kinase cAMP-dependent type I regulatory subunit beta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PRKAR1
Description (Vector)
Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP.(supplied by OMIM, Jun 2009)
Gene ID
5575
Gene Name (Vector)
protein kinase cAMP-dependent type I regulatory subunit beta
Gene Symbol
PRKAR1B
HGNC ID
HGNC:9390
ORF Size (aa)
1146
ORF Size (bp)
1146 bp
RefSeq ID
NM_002735
RefSeq Synonyms
NM_002735, NM_001164762, NM_001164761, NM_001164760, NM_001164759, NM_001164758, BC036828, BC026734,
Species
human
UniGene ID
Hs.520851
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.