human PPP4R2 shRNA silencing AAV

Name 
AAV-h-PPP4R2-shRNA
Cat No 
shAAV-219684
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PPP4R2.

shAAV-219684
AAV-h-PPP4R2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PPP4R2 (protein phosphatase 4 regulatory subunit 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
Description (eCommerce)
PPP4R2 is a regulatory subunit associated with the PP4 serine/threonine protein phosphatase catalytic subunit PPP4C. PPP4C is structurally related to PP2AC but does not associate with the same regulatory subunits. PPP4C associates with either the PPP4R1 or PPP4R2 regulatory subunit. PPP4R2 has been shown to localize to centrosomes and may function in targeting PPP4C to microtubule organizing centers.
Gene ID
151987
Gene Name (eCommerce)
protein phosphatase 4 regulatory subunit 2
Gene Name (Vector)
protein phosphatase 4 regulatory subunit 2
Gene Symbol
PPP4R2
HGNC ID
HGNC:18296
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1254
ORF Size (bp)
1254 bp
Protein Name (eCommerce)
Serine/threonine-protein phosphatase 4 regulatory subunit 2
RefSeq ID
NM_174907
RefSeq Synonyms
NM_174907, NM_001318028, NM_001318027, NM_001318026, NM_001318025, BC128137, BC128136, BC110889,
Research Areas
Cytoskeleton,DNA Damage/Repair,Kinase/Phosphatase,mRNA Processing,mRNA Splicing,RNA Processing
Research Areas (Faceted)
cell_biology,genetics,signal_transduction,transcription_translation
Species
human
Target Sentence
PPP4R2 is a regulatory subunit associated with the PP4 serine/threonine protein phosphatase catalytic subunit PPP4C. PPP4C is structurally related to PP2AC but does not associate with the same regulatory subunits. PPP4C associates with either the PPP4R1 or PPP4R2 regulatory subunit. PPP4R2 has been shown to localize to centrosomes and may function in targeting PPP4C to microtubule organizing centers.
UniGene ID
Hs.431092
UniProt ID (eCommerce)
Q9NY27

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.