human PPP1R3A shRNA silencing AAV

Name
AAV-h-PPP1R3A-shRNA

Cat No
shAAV-219633

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human PPP1R3A.

shAAV-219633

AAV-h-PPP1R3A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PPP1R3A (protein phosphatase 1 regulatory subunit 3A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

GM; PP1G; PPP1R3

Description (Vector)

The glycogen-associated form of protein phosphatase-1 (PP1) derived from skeletal muscle is a heterodimer composed of a 37-kD catalytic subunit and a 124-kD targeting and regulatory subunit. This gene encodes the regulatory subunit which binds to muscle glycogen with high affinity, thereby enhancing dephosphorylation of glycogen-bound substrates for PP1 such as glycogen synthase and glycogen phosphorylase kinase.

Gene ID

5506

Gene Name (Vector)

protein phosphatase 1 regulatory subunit 3A

Gene Symbol

PPP1R3A

HGNC ID

HGNC:9291

ORF Size (aa)

3369

ORF Size (bp)

3369 bp

RefSeq ID

NM_002711

RefSeq Synonyms

NM_002711, BC126453, BC126451, BC111452,

Species

human

UniGene ID

Hs.458309

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.