human PPIB shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PPIB.
shAAV-219549
AAV-h-PPIB-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PPIB (peptidylprolyl isomerase B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CYP-S1; CYPB; HEL-S-39; OI9; SCYLP
Description (Vector)
PPIB is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.
Gene ID
5479
Gene Name (Vector)
peptidylprolyl isomerase B
Gene Symbol
PPIB
HGNC ID
HGNC:9255
ORF Size (aa)
651
RefSeq ID
NM_000942
RefSeq Synonyms
NM_000942, BC032138, BC020800, BC008848, BC001125,
Species
human
UniGene ID
Hs.434937
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.