human PPCS shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PPCS.
shAAV-219519
AAV-h-PPCS-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PPCS (phosphopantothenoylcysteine synthetase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCS (EC 6.3.2.5), one of the last enzymes in this pathway, converts phosphopantothenate to phosphopantothenoylcysteine (Daugherty et al., 2002 (PubMed 11923312)).(supplied by OMIM, Mar 2008)
Gene ID
79717
Gene Name (Vector)
phosphopantothenoylcysteine synthetase
Gene Symbol
PPCS
HGNC ID
HGNC:25686
ORF Size (aa)
936
ORF Size (bp)
936 bp
RefSeq ID
NM_024664
RefSeq Synonyms
NM_024664, NM_001287511, NM_001287510, NM_001287509, NM_001287508, NM_001287507, NM_001287506, NM_001077447, BC112015, BC106064, BC104938,
Species
human
UniGene ID
Hs.710166
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.