human POU3F4 shRNA silencing AAV

Name
AAV-h-POU3F4-shRNA

Cat No
shAAV-219480

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human POU3F4.

shAAV-219480

AAV-h-POU3F4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human POU3F4 (POU class 3 homeobox 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BRAIN-4; BRN-4; BRN4; DFN3; DFNX2; OCT-9; OTF-9; OTF9

Description (Vector)

POU3F4 encodes a member of the POU-III class of neural transcription factors. POU3F4 may play a role in the mediation of epigenetic signals which induce striatal neuron-precursor differentiation. Mutations have been associated with X chromosome-linked nonsyndromic mixed deafness.

Gene ID

5456

Gene Name (Vector)

POU class 3 homeobox 4

Gene Symbol

POU3F4

HGNC ID

HGNC:9217

ORF Size (aa)

1083

ORF Size (bp)

1083 bp

RefSeq ID

NM_000307

RefSeq Synonyms

NM_000307, BC146551, BC141561,

Species

human

UniGene ID

Hs.2229

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.