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human POLR3C shRNA silencing AAV

Name 
AAV-h-POLR3C-shRNA
Cat No 
shAAV-219415
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human POLR3C.

shAAV-219415
AAV-h-POLR3C-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human POLR3C (RNA polymerase III subunit C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DNA-directed III 62 kDa polypeptide; DNA-directed RNA polymerase III subunit C; DNA-directed RNA polymerase III subunit RPC3; polymerase (RNA) III (DNA directed) polypeptide C (62kD); polymerase (RNA) III subunit C; RNA polymerase III 62 kDa subunit; RNA polymerase III subunit C3; RPC3; RPC62
Description (eCommerce)
RNA polymerase III subunit C (RPC3) encodes one of 17 subunits of the RNA polymerase III (PolIII) which synthesizes small RNAs, such as 5S rRNA and tRNA. The protein is encoded by the POLR3D gene.
Gene ID
10623
Gene Name (eCommerce)
RNA polymerase III subunit C
Gene Name (Vector)
RNA polymerase III subunit C
Gene Symbol
POLR3C
HGNC ID
HGNC:30076
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1605
ORF Size (bp)
1605 bp
Protein Name (eCommerce)
DNA-directed RNA polymerase III subunit RPC3
RefSeq ID
NM_006468
RefSeq Synonyms
NM_006468, NM_001303456, BC004424, BC002586,
Research Areas
Gene Expression,Host-Virus Interactions,Immunology,Innate Immunity,Response to Virus,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,immunology,infectious_disease,transcription_translation
Species
human
Target Sentence
RNA polymerase III subunit C (RPC3) encodes one of 17 subunits of the RNA polymerase III (PolIII) which synthesizes small RNAs, such as 5S rRNA and tRNA. The protein is encoded by the POLR3D gene.
UniGene ID
Hs.591457
UniProt ID (eCommerce)
Q9BUI4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.