human POLR2B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human POLR2B.
shAAV-219387
AAV-h-POLR2B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human POLR2B (RNA polymerase II subunit B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
hRPB140; POL2RB; RPB2
Description (Vector)
POLR2B encodes the second largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with at least two other polymerase subunits, forms a structure within the polymerase that maintains contact in the active site of the enzyme between the DNA template and the newly synthesized RNA.
Gene ID
5431
Gene Name (Vector)
RNA polymerase II subunit B
Gene Symbol
POLR2B
HGNC ID
HGNC:9188
ORF Size (aa)
3525
ORF Size (bp)
3525 bp
RefSeq ID
NM_000938
RefSeq Synonyms
NM_001303269, NM_001303268, NM_000938, BC023503,
Species
human
UniGene ID
Hs.602757
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.