human PNKD shRNA silencing AAV

Name
AAV-h-PNKD-shRNA

Cat No
shAAV-219286

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human PNKD.

shAAV-219286

AAV-h-PNKD-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PNKD (paroxysmal nonkinesigenic dyskinesia). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BRP17; DYT8; FKSG19; FPD1; KIPP1184; MR-1; MR1; PDC; PKND1; TAHCCP2

Description (Vector)

PNKD is thought to play a role in the regulation of myofibrillogenesis. Mutations in this gene have been associated with the movement disorder paroxysmal non-kinesigenic dyskinesia. Alternative splicing results in multiple transcript variants.

Gene ID

25953

Gene Name (Vector)

paroxysmal nonkinesigenic dyskinesia

Gene Symbol

PNKD

HGNC ID

HGNC:9153

ORF Size (aa)

1158

ORF Size (bp)

1158 bp

RefSeq ID

NM_015488

RefSeq Synonyms

NM_022572, NM_015488, NM_001077399, BC036457, BC002937,

Species

human

UniGene ID

Hs.98475

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.