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human PMEPA1 shRNA silencing AAV

Name 
AAV-h-PMEPA1-shRNA
Cat No 
shAAV-219265
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PMEPA1.

shAAV-219265
AAV-h-PMEPA1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PMEPA1 (prostate transmembrane protein, androgen induced 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
STAG1; TMEPAI
Description (Vector)
PMEPA1 encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
56937
Gene Name (Vector)
prostate transmembrane protein, androgen induced 1
Gene Symbol
PMEPA1
HGNC ID
HGNC:14107
ORF Size (aa)
759
RefSeq ID
NM_020182
RefSeq Synonyms
NM_199171, NM_199170, NM_199169, NM_020182, NM_001255976, BC080635,
Species
human
UniGene ID
Hs.517155

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.