human PLS1 shRNA silencing AAV

Name
AAV-h-PLS1-shRNA

Cat No
shAAV-219226

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human PLS1.

shAAV-219226

AAV-h-PLS1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PLS1 (plastin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. The protein encoded by this gene is a third distinct plastin isoform, which is specifically expressed at high levels in the small intestine. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene. A pseudogene of this gene is found on chromosome 11.

Gene ID

5357

Gene Name (Vector)

plastin 1

Gene Symbol

PLS1

HGNC ID

HGNC:9090

ORF Size (aa)

1890

ORF Size (bp)

1890 bp

RefSeq ID

NM_002670

RefSeq Synonyms

NM_002670, NM_001172312, NM_001145319, BC031083,

Species

human

UniGene ID

Hs.203637

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.