human PLP2 shRNA silencing AAV

Name 
AAV-h-PLP2-shRNA
Cat No 
shAAV-219223
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PLP2.

shAAV-219223
AAV-h-PLP2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PLP2 (proteolipid protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
A4; A4LSB
Description (Vector)
PLP2 encodes an integral membrane protein that localizes to the endoplasmic reticulum in colonic epithelial cells. The encoded protein can multimerize and may function as an ion channel. A polymorphism in the promoter of this gene may be linked to an increased risk of X-linked mental retardation. A pseudogene of this gene is found on chromosome 5.
Gene ID
5355
Gene Name (Vector)
proteolipid protein 2
Gene Symbol
PLP2
HGNC ID
HGNC:9087
ORF Size (aa)
459
RefSeq ID
NM_002668
RefSeq Synonyms
NM_002668, BC109066,
Species
human
UniGene ID
Hs.77422

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.