human PLCB3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PLCB3.
shAAV-219118
AAV-h-PLCB3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PLCB3 (phospholipase C beta 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3; phosphoinositide phospholipase C-beta-3; phospholipase C, beta 3 (phosphatidylinositol-specific); Phospholipase C-beta-3; PLC beta 3; PLC-beta-3
Description (eCommerce)
PLCB3 is a member of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction [taken from NCBI Entrez Gene (Gene ID: 5331)].
Description (Vector)
PLCB3 encodes a member of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction. Alternative splicing results in multiple transcript variants.
Gene ID
5331
Gene Name (eCommerce)
phospholipase C beta 3
Gene Name (Vector)
phospholipase C beta 3
Gene Symbol
PLCB3
HGNC ID
HGNC:9056
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3705
ORF Size (bp)
3705 bp
Protein Name (eCommerce)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
RefSeq ID
NM_000932
RefSeq Synonyms
NM_001316314, NM_001184883, NM_000932, BC142681,
Research Areas
Alzheimer's Disease,Cardiology,Cardiovascular,Estrogen Signaling,GnRH Signaling,Golgi Apparatus,GPCR Signaling,Huntington's Disease,Interleukin Signaling,MAPK Signaling,Metabolism/Metabolic Process,Neurobiology,Neurodegeneration,Signal Transduction,Wnt Signaling
Research Areas (Faceted)
cardiovascular,cell_biology,immunology,metabolism,neurobiology,signal_transduction
Species
human
Target Sentence
PLCB3 is a member of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction [taken from NCBI Entrez Gene (Gene ID: 5331)].
UniGene ID
Hs.591953
UniProt ID (eCommerce)
Q01970
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.