human PLA2G4C shRNA silencing AAV

Name
AAV-h-PLA2G4C-shRNA

Cat No
shAAV-219072

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human PLA2G4C.

shAAV-219072

AAV-h-PLA2G4C-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PLA2G4C (phospholipase A2 group IVC). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CPLA2-gamma

Description (Vector)

PLA2G4C encodes a protein which is a member of the phospholipase A2 enzyme family which hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids, both of which serve as precursors in the production of signaling molecules. The encoded protein has been shown to be a calcium-independent and membrane bound enzyme. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID

8605

Gene Name (Vector)

phospholipase A2 group IVC

Gene Symbol

PLA2G4C

HGNC ID

HGNC:9037

ORF Size (aa)

1626

ORF Size (bp)

1626 bp

RefSeq ID

NM_003706

RefSeq Synonyms

NM_003706, NM_001159323, NM_001159322, BC063416,

Species

human

UniGene ID

Hs.631562

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.