human PKP3 shRNA silencing AAV

Name 
AAV-h-PKP3-shRNA
Cat No 
shAAV-219049
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PKP3.

shAAV-219049
AAV-h-PKP3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PKP3 (plakophilin 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
PKP3 encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways.
Gene ID
11187
Gene Name (Vector)
plakophilin 3
Gene Symbol
PKP3
HGNC ID
HGNC:9025
ORF Size (aa)
2394
ORF Size (bp)
2394 bp
RefSeq ID
NM_007183
RefSeq Synonyms
NM_007183, NM_001303029, BC000081,
Species
human
UniGene ID
Hs.534395

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.