human PIN4 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PIN4.
shAAV-218973
AAV-h-PIN4-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PIN4 (peptidylprolyl cis/trans isomerase, NIMA-interacting 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EPVH; eukaryotic parvulin homolog; hEPVH; hPar14; hPar17; PAR14; PAR17; parvulin; parvulin-14; parvulin-17; peptidyl-prolyl cis/trans isomerase EPVH; peptidyl-prolyl cis-trans isomerase NIMA-interacting 4; peptidyl-prolyl cis-trans isomerase Pin4; PPIase PIN4; protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin); rotamase PIN4
Description (eCommerce)
PIN4 is a member of the parvulin subfamily of the peptidyl-prolyl cis/trans isomerase protein family. The encoded protein catalyzes the isomerization of peptidylprolyl bonds, and may play a role in the cell cycle, chromatin remodeling, and/or ribosome biogenesis. PIN4 may play an additional role in the mitochondria [taken from NCBI Entrez Gene (Gene ID: 5303)].
Description (Vector)
PIN4 encodes a member of the parvulin subfamily of the peptidyl-prolyl cis/trans isomerase protein family. The encoded protein catalyzes the isomerization of peptidylprolyl bonds, and may play a role in the cell cycle, chromatin remodeling, and/or ribosome biogenesis. The encoded protein may play an additional role in the mitochondria.
Gene ID
5303
Gene Name (eCommerce)
peptidylprolyl cis/trans isomerase, NIMA-interacting 4
Gene Name (Vector)
peptidylprolyl cis/trans isomerase, NIMA-interacting 4
Gene Symbol
PIN4
HGNC ID
HGNC:8992
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
471
Protein Name (eCommerce)
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4
RefSeq ID
NM_006223
RefSeq Synonyms
NM_006223, NM_001170747, BC112281, BC093700,
Research Areas
Cell Cycle,Cytoskeleton,Mitochondrion,Protein Folding,RNA Processing
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
PIN4 is a member of the parvulin subfamily of the peptidyl-prolyl cis/trans isomerase protein family. The encoded protein catalyzes the isomerization of peptidylprolyl bonds, and may play a role in the cell cycle, chromatin remodeling, and/or ribosome biogenesis. PIN4 may play an additional role in the mitochondria [taken from NCBI Entrez Gene (Gene ID: 5303)].
UniGene ID
Hs.655623
UniProt ID (eCommerce)
Q9Y237
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.