human PIM3 shRNA silencing AAV

Name 
AAV-h-PIM3-shRNA
Cat No 
shAAV-218971
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PIM3.

shAAV-218971
AAV-h-PIM3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PIM3 (Pim-3 proto-oncogene, serine/threonine kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
pim-3
Description (Vector)
PIM3 belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is overexpressed in hematological and epithelial tumors and is associated with MYC coexpression. It plays a role in the regulation of signal transduction cascades, contributing to both cell proliferation and survival, and provides a selective advantage in tumorigenesis.
Gene ID
415116
Gene Name (Vector)
Pim-3 proto-oncogene, serine/threonine kinase
Gene Symbol
PIM3
HGNC ID
HGNC:19310
ORF Size (aa)
981
ORF Size (bp)
981 bp
RefSeq ID
NM_001001852
RefSeq Synonyms
NM_001001852, BC141855, BC140030,
Species
human
UniGene ID
Hs.530381

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.