human PIK3CD shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PIK3CD.
shAAV-218949
AAV-h-PIK3CD-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PIK3CD (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
APDS; IMD14; p110D; P110DELTA; PI3K
Description (Vector)
Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.
Gene ID
5293
Gene Name (Vector)
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
Gene Symbol
PIK3CD
HGNC ID
HGNC:8977
ORF Size (aa)
3135
ORF Size (bp)
3135 bp
RefSeq ID
NM_005026
RefSeq Synonyms
NM_005026, BC150297, BC144264, BC132921, BC132919,
Species
human
UniGene ID
Hs.518451
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.