human PIK3CD shRNA silencing AAV

Name 
AAV-h-PIK3CD-shRNA
Cat No 
shAAV-218949
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PIK3CD.

shAAV-218949
AAV-h-PIK3CD-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PIK3CD (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
APDS; IMD14; p110D; P110DELTA; PI3K
Description (Vector)
Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.
Gene ID
5293
Gene Name (Vector)
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
Gene Symbol
PIK3CD
HGNC ID
HGNC:8977
ORF Size (aa)
3135
ORF Size (bp)
3135 bp
RefSeq ID
NM_005026
RefSeq Synonyms
NM_005026, BC150297, BC144264, BC132921, BC132919,
Species
human
UniGene ID
Hs.518451

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.