human PIK3C2G shRNA silencing AAV

Name
AAV-h-PIK3C2G-shRNA

Cat No
shAAV-218942

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human PIK3C2G.

shAAV-218942

AAV-h-PIK3C2G-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PIK3C2G (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

PI3K-C2-gamma; PI3K-C2GAMMA

Description (Vector)

PIK3C2G belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The biological function of this gene has not yet been determined.

Gene ID

5288

Gene Name (Vector)

phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma

Gene Symbol

PIK3C2G

HGNC ID

HGNC:8973

ORF Size (aa)

4335

ORF Size (bp)

4335 bp

RefSeq ID

NM_004570

RefSeq Synonyms

NM_004570, NM_001288774, NM_001288772, BC144134, BC130277,

Species

human

UniGene ID

Hs.22500

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.