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human PIGQ shRNA silencing AAV

Name 
AAV-h-PIGQ-shRNA
Cat No 
shAAV-218919
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PIGQ.

shAAV-218919
AAV-h-PIGQ-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PIGQ (phosphatidylinositol glycan anchor biosynthesis class Q). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
c407A10.1; GPI1
Description (Vector)
PIGQ is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. PIGQ encodes a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
9091
Gene Name (Vector)
phosphatidylinositol glycan anchor biosynthesis class Q
Gene Symbol
PIGQ
HGNC ID
HGNC:14135
ORF Size (aa)
2283
ORF Size (bp)
2283 bp
RefSeq ID
NM_004204
RefSeq Synonyms
NM_148920, NM_004204, BC006377,
Species
human
UniGene ID
Hs.709562

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.