human PIGP shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PIGP.
shAAV-218917
AAV-h-PIGP-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PIGP (phosphatidylinositol glycan anchor biosynthesis class P). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DCRC; DCRC-S; DSCR5; DSRC; PIG-P
Description (Vector)
PIGP encodes an enzyme involved in the first step of glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. The encoded protein is a component of the GPI-N-acetylglucosaminyltransferase complex that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). PIGP is located in the Down Syndrome critical region on chromosome 21 and is a candidate for the pathogenesis of Down syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene ID
51227
Gene Name (Vector)
phosphatidylinositol glycan anchor biosynthesis class P
Gene Symbol
PIGP
HGNC ID
HGNC:3046
ORF Size (aa)
405
RefSeq ID
NM_153681
RefSeq Synonyms
NM_153682, NM_153681, NM_016430, NM_001320480, BC011007, BC005180,
Species
human
UniGene ID
Hs.716087
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.