human PIAS3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PIAS3.
shAAV-218888
AAV-h-PIAS3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PIAS3 (protein inhibitor of activated STAT 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ZMIZ5
Description (Vector)
PIAS3 encodes a member of the PIAS (protein inhibitor of activated STAT (signal transducer and activator of transcription)) family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined.
Gene ID
10401
Gene Name (Vector)
protein inhibitor of activated STAT 3
Gene Symbol
PIAS3
HGNC ID
HGNC:16861
ORF Size (aa)
1887
ORF Size (bp)
1887 bp
RefSeq ID
NM_006099
RefSeq Synonyms
NM_006099, BC030556, BC001154,
Species
human
UniGene ID
Hs.435761
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.