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human PHLDB2 shRNA silencing AAV

Name 
AAV-h-PHLDB2-shRNA
Cat No 
shAAV-218848
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PHLDB2.

shAAV-218848
AAV-h-PHLDB2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PHLDB2 (pleckstrin homology like domain family B member 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
LL5 beta; LL5b; LL5beta; pleckstrin homology-like domain family B member 2; protein LL5-beta
Description (eCommerce)
Pleckstrin homology-like domain family B member 2 (LL5beata) seems to be involved in the assembly of the postsynaptic apparatus. LL5beta may play a role in acetyl-choline receptor (AChR) aggregation in the postsynaptic membrane (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q86SQ0].
Gene ID
90102
Gene Name (eCommerce)
pleckstrin homology like domain family B member 2
Gene Name (Vector)
pleckstrin homology like domain family B member 2
Gene Symbol
PHLDB2
HGNC ID
HGNC:29573
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3762
ORF Size (bp)
3762 bp
Protein Name (eCommerce)
Pleckstrin homology-like domain family B member 2
RefSeq ID
NM_145753
RefSeq Synonyms
NM_145753, NM_001134439, NM_001134438, NM_001134437, BC150210, BC142678,
Research Areas
Cytoskeleton,EGFR Signaling,Signal Transduction
Research Areas (Faceted)
signal_transduction,cell_biology
Species
human
Target Sentence
Pleckstrin homology-like domain family B member 2 (LL5beata) seems to be involved in the assembly of the postsynaptic apparatus. LL5beta may play a role in acetyl-choline receptor (AChR) aggregation in the postsynaptic membrane (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q86SQ0].
UniGene ID
Hs.679140
UniProt ID (eCommerce)
Q86SQ0

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.