human PHLDA2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PHLDA2.
shAAV-218844
AAV-h-PHLDA2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PHLDA2 (pleckstrin homology like domain family A member 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BRW1C; BWR1C; HLDA2; IPL; TSSC3
Description (Vector)
PHLDA2 is located in a cluster of imprinted genes on chromosome 11p15.5, which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. PHLDA2 has been shown to be imprinted, with preferential expression from the maternal allele in placenta and liver.
Gene ID
7262
Gene Name (Vector)
pleckstrin homology like domain family A member 2
Gene Symbol
PHLDA2
HGNC ID
HGNC:12385
ORF Size (aa)
459
RefSeq ID
NM_003311
RefSeq Synonyms
NM_003311, BC005034,
Species
human
UniGene ID
Hs.154036
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.