human PHC1 shRNA silencing AAV

Name 
AAV-h-PHC1-shRNA
Cat No 
shAAV-218789
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PHC1.

shAAV-218789
AAV-h-PHC1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PHC1 (polyhomeotic homolog 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EDR1; HPH1; MCPH11; RAE28
Description (Vector)
PHC1 is a homolog of the Drosophila polyhomeotic gene, which is a member of the Polycomb group of genes. The gene product is a component of a multimeric protein complex that contains EDR2 and the vertebrate Polycomb protein BMH1. The gene product, the EDR2 protein, and the Drosophila polyhomeotic protein share 2 highly conserved domains, named homology domains I and II. These domains are involved in protein-protein interactions and may mediate heterodimerization of the protein encoded by this gene and the EDR2 protein.
Gene ID
1911
Gene Name (Vector)
polyhomeotic homolog 1
Gene Symbol
PHC1
HGNC ID
HGNC:3182
ORF Size (aa)
2874
ORF Size (bp)
2874 bp
RefSeq ID
NM_004426
RefSeq Synonyms
NM_004426, BC157850, BC073964, BC017748,
Species
human
UniGene ID
Hs.305985

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.