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human PGAP1 shRNA silencing AAV

Name 
AAV-h-PGAP1-shRNA
Cat No 
shAAV-218723
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PGAP1.

shAAV-218723
AAV-h-PGAP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PGAP1 (post-GPI attachment to proteins 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
50
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Bst1; ISPD3024; MRT42; SPG67
Description (Vector)
PGAP1 catalyzes the inositol deacylation of glycosylphosphatidylinositol (GPI) at an early step in GPI biosynthesis. Inositol deacylation is essential for the generation of mature GPI capable of attachment to proteins (Tanaka et al., 2004 (PubMed 14734546)).(supplied by OMIM, Mar 2008)
Gene ID
80055
Gene Name (Vector)
post-GPI attachment to proteins 1
Gene Symbol
PGAP1
HGNC ID
HGNC:25712
ORF Size (aa)
2766
ORF Size (bp)
2766 bp
RefSeq ID
NM_024989
RefSeq Synonyms
NM_024989, NM_001321100, NM_001321099, BC152719,
Species
human
UniGene ID
Hs.229988

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.