human PFN2 shRNA silencing AAV

Name 
AAV-h-PFN2-shRNA
Cat No 
shAAV-218695
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PFN2.

shAAV-218695
AAV-h-PFN2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PFN2 (profilin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
D3S1319E; PFL
Description (Vector)
PFN2 is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene.
Gene ID
5217
Gene Name (Vector)
profilin 2
Gene Symbol
PFN2
HGNC ID
HGNC:8882
ORF Size (aa)
423
RefSeq ID
NM_053024
RefSeq Synonyms
NM_053024, NM_002628, BC095444, BC043646, BC018049,
Species
human
UniGene ID
Hs.91747

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.